A successful collaboration within the SEA-EU Alliance between the University of Split School of Medicine (UNIST) and the University of Brest (UBO) has resulted in a publication in the Journal of Clinical Epidemiology, one of the leading international journals in the field of clinical research methodology.
The collaboration began in the summer of 2023, when Glenn Goasdoué, a medical student from the University of Brest, spent one month at the Center for Evidence-Based Medicine at the University of Split School of Medicine. His stay was carried out within the framework of SEA-EU cooperation and was supervised by Prof. Ana Marušić, MD, PhD, with scientific leadership provided by Prof. Marija Franka Žuljević, MD, PhD, from the Department of Medical Humanities.
During his research stay in Split, the student contributed to a study examining the consistency of reporting protocols and adverse events in clinical trials of two psychedelic substances currently being investigated as potential psychiatric treatments. The research team compared data reported in the ClinicalTrials.gov registry with corresponding scientific publications.
The analysis revealed that a substantial proportion of clinical trials modified their primary outcomes and inclusion criteria after participant enrolment, often without transparently reporting these changes in published articles. In addition, many trials failed to publish their results in a timely manner, and the reporting of adverse events frequently differed between trial registries and journal publications.
The authors conclude that such inconsistencies undermine the credibility of research findings and hinder reliable safety assessments of psychedelic therapies. The study highlights the urgent need for greater transparency and stricter reporting standards in clinical research.
The results of this SEA-EU collaboration have now been published in the Journal of Clinical Epidemiology, confirming the scientific value of student mobility and cross-institutional cooperation within the alliance.
This collaboration illustrates the core mission of the SEA-EU Alliance by creating valuable opportunities for young researchers through international cooperation and student mobility. At the same time, it represents a highly rewarding experience for academic staff, enabling mentors and supervisors to engage in meaningful cross-institutional collaboration, exchange expertise, and jointly contribute to high-quality, impactful research across Europe.
🔗 Read the article:
https://www.jclinepi.com/article/S0895-4356(26)00045-4/abstract
https://www.sciencedirect.com/science/article/abs/pii/S0895435626000454
